MCU Monoclonal Antibody
- SKU:
- CAB22525
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | MCU Monoclonal Antibody |
| Product Code: | CAB22525 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57879 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:20000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, 293T, NIH/3T3, Mouse spleen, Rat skeletal muscle |
| Cellular Location: | mitochondrial inner membrane, mitochondrion |
Enables calcium channel activity; identical protein binding activity; and uniporter activity. Involved in several processes, including positive regulation of mitochondrial calcium ion concentration; positive regulation of mitochondrial fission; and positive regulation of neutrophil chemotaxis. Acts upstream of or within calcium import into the mitochondrion. Located in mitochondrial inner membrane. Is integral component of mitochondrial inner membrane. Part of uniplex complex.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 51-170 of human MCU (NP_612366.1). |
| Sequence: | VHQRI ASWQN LGAVY CSTVV PSDDV TVVYQ NGLPV ISVRL PSRRE RCQFT LKPIS DSVGV FLRQL QEEDR GIDRV AIYSP DGVRV AASTG IDLLL LDDFK LVIND LTYHV RPPKR DLLSH |
| Synonyms: | HsMCU, C10orf42, CCDC109A |
| Calculated MW: | 40kDa |
| Observed MW: | Refer to figures |
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