Antibody Name:	MAP1A Antibody (PACO18950)
Antibody SKU:	PACO18950
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:3000-1:10000, IHC:1:50-1:200
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human MAP1A

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18950(MAP1A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18950(MAP1A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development.

Synonyms:

microtubule-associated protein 1A

UniProt Protein Function:	MAP1A: structural protein involved in the filamentous cross- bridging between microtubules and other skeletal elements. Various serine residues may be phosphorylated by PKA.Protein type: Motility/polarity/chemotaxis; CytoskeletalChromosomal Location of Human Ortholog: 15q15.3Cellular Component: microtubule; microtubule associated complex; cytosolMolecular Function: protein binding; microtubule binding; structural molecule activityBiological Process: sensory perception of sound; microtubule cytoskeleton organization and biogenesis
UniProt Protein Details:
NCBI Summary:	This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development. [provided by RefSeq, Jul 2008]
UniProt Code:	P78559
NCBI GenInfo Identifier:	313104325
NCBI Gene ID:	4130
NCBI Accession:	P78559.6
UniProt Secondary Accession:	P78559,O95643, Q12973, Q15882, Q9UJT4
UniProt Related Accession:	P78559
Molecular Weight:	305,671 Da
NCBI Full Name:	Microtubule-associated protein 1A
NCBI Synonym Full Names:	microtubule-associated protein 1A
NCBI Official Symbol:	MAP1A
NCBI Official Synonym Symbols:	MAP1L; MTAP1A
NCBI Protein Information:	microtubule-associated protein 1A; MAP-1A; proliferation-related protein p80
UniProt Protein Name:	Microtubule-associated protein 1A
UniProt Synonym Protein Names:	Proliferation-related protein p80Cleaved into the following 2 chains:MAP1A heavy chain; MAP1 light chain LC2
Protein Family:	Methionine aminopeptidase
UniProt Gene Name:	MAP1A
UniProt Entry Name:	MAP1A_HUMAN