Lrwd1 Polyclonal Antibody
- SKU:
- CAB21399
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Lrwd1 Polyclonal Antibody |
| Product Code: | CAB21399 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | Chromosome, Cytoplasm, Nucleus, centromere, centrosome, cytoskeleton, microtubule organizing center, telomere |
The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human Lrwd1 (NP_690852.1). |
| Sequence: | ASPSA QVEGS PVAGS DGSQP AVKLE PLHFL QCHSK NNSPQ DLETQ LWACA FEPAW EEGAT SQTVA TCGGE AVCVI DCQTG IVLHK YKAPG EEFFS VAWTA L |
| Synonyms: | ORCA, CENP-33 |
| Calculated MW: | 71kDa |
| Observed MW: | Refer to figures |
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