LRP12 Antibody (PACO14655)
- SKU:
- PACO14655
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | LRP12 Antibody (PACO14655) |
| Antibody SKU: | PACO14655 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human LRP12 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO14655(LRP12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO14655(LRP12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants. |
| Synonyms: | low density lipoprotein receptor-related protein 12 |
| UniProt Protein Function: | LRP12: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor. Belongs to the LDLR family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 8q22.2 Cellular Component: integral to plasma membrane Molecular Function:protein binding |
| NCBI Summary: | This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] |
| UniProt Code: | Q9Y561 |
| NCBI GenInfo Identifier: | 25091287 |
| NCBI Gene ID: | 29967 |
| NCBI Accession: | Q9Y561.1 |
| UniProt Secondary Accession: | Q9Y561,A8K137, B4DRQ2, |
| UniProt Related Accession: | Q9Y561 |
| Molecular Weight: | 93,123 Da |
| NCBI Full Name: | Low-density lipoprotein receptor-related protein 12 |
| NCBI Synonym Full Names: | LDL receptor related protein 12 |
| NCBI Official Symbol: | LRP12 |
| NCBI Official Synonym Symbols: | ST7 |
| NCBI Protein Information: | low-density lipoprotein receptor-related protein 12 |
| UniProt Protein Name: | Low-density lipoprotein receptor-related protein 12 |
| UniProt Synonym Protein Names: | Suppressor of tumorigenicity 7 protein |
| Protein Family: | Low-density lipoprotein receptor-related protein |
| UniProt Gene Name: | LRP12 |
| UniProt Entry Name: | LRP12_HUMAN |
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