LGR5 Polyclonal Antibody
- SKU:
- CAB24460
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | LGR5 Polyclonal Antibody |
| Product Code: | CAB24460 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse brain |
| Cellular Location: | Cell membrane, Golgi apparatus, Multi-pass membrane protein, trans-Golgi network membrane |
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 480-580 of human LGR5 (NP_003658.1). |
| Sequence: | CAFGV CENAY KISNQ WNKGD NSSMD DLHKK DAGMF QAQDE RDLED FLLDF EEDLK ALHSV QCSPS PGPFK PCEHL LDGWL IRIGV WTIAV LALTC NALVT S |
| Synonyms: | FEX, HG38, GPR49, GPR67, GRP49 |
| Observed MW: | 102kDa |
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