LCT Polyclonal Antibody
- SKU:
- CAB10566
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | LCT Polyclonal Antibody |
| Product Code: | CAB10566 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Apical cell membrane, Single-pass type I membrane protein |
The protein encoded by this gene belongs to the glycosyl hydrolase 1 family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme is integral to the plasma membrane and has both phlorizin hydrolase activity and lactase activity. Mutations in this gene are associated with congenital lactase deficiency. Polymorphisms in this gene are associated with lactase persistence, in which intestinal lactase activity persists at childhood levels into adulthood.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1580-1870 of human LCT (NP_002290.2). |
| Sequence: | HLYND VYRAS QGGVI SITIS SDWAE PRDPS NQEDV EAARR YVQFM GGWFA HPIFK NGDYN EVMKT RIRDR SLAAG LNKSR LPEFT ESEKR RINGT YDFFG FNHYT TVLAY NLNYA TAISS FDADR GVASI ADRSW PDSGS FWLKM TPFGF RRILN WLKEE YNDPP IYVTE NGVSQ REETD LNDTA RIYYL RTYIN EALKA VQDKV DLRGY TVWSA MDNFE WATGF SERFG LHFVN YSDPS LPRIP KASAK FYASV VRCNG FPDPA TGPHA CLHQP DAGPT ISPVR QEEVQ F |
| Synonyms: | LAC, LPH, LPH1 |
| Calculated MW: | 219kDa |
| Observed MW: | Refer to figures |
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