LAMTOR2 Polyclonal Antibody
- SKU:
- CAB20857
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | LAMTOR2 Polyclonal Antibody |
| Product Code: | CAB20857 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | late endosome, plasma membrane |
The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human LAMTOR2 (NP_054736.1). |
| Sequence: | MLRPK ALTQV LSQAN TGGVQ STLLL NNEGS LLAYS GYGDT DARVT AAIAS NIWAA YDRNG NQAFN EDNLK FILMD CMEGR VAITR VANLL LCMYA KETVG FGMLK AKAQA LVQYL EEPLT QVAAS |
| Synonyms: | p14, ENDAP, ROBLD3, HSPC003, MAPBPIP, MAPKSP1AP, Ragulator2 |
| Calculated MW: | 14kDa |
| Observed MW: | Refer to figures |
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