Description
| Product Name: | Lamin B1 Polyclonal Antibody |
| Product Code: | CAB2452 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | Lipid-anchor, Nucleoplasmic side, Nucleus inner membrane |
This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-500 of human Lamin B1 (NP_005564.1). |
| Sequence: | VSRAS SSRSV RTTRG KRKRV DVEES EASSS VSISH SASAT GNVCI EEIDV DGKFI RLKNT SEQDQ PMGGW EMIRK IGDTS VSYKY TSRYV LKAGQ TVTIW A |
| Synonyms: | LMN, ADLD, LMN2, LMNB, MCPH26 |
| Calculated MW: | 66kDa |
| Observed MW: | 66kDa |