Description
Product Name: | Lamin B1 Polyclonal Antibody |
Product Code: | CAB2452 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Positive Samples: | HeLa |
Cellular Location: | Lipid-anchor, Nucleoplasmic side, Nucleus inner membrane |
This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-500 of human Lamin B1 (NP_005564.1). |
Sequence: | VSRAS SSRSV RTTRG KRKRV DVEES EASSS VSISH SASAT GNVCI EEIDV DGKFI RLKNT SEQDQ PMGGW EMIRK IGDTS VSYKY TSRYV LKAGQ TVTIW A |
Synonyms: | LMN, ADLD, LMN2, LMNB, MCPH26 |
Calculated MW: | 66kDa |
Observed MW: | 66kDa |