Description
Product Name: | L3MBTL3 Monoclonal Antibody |
Product Code: | CAB21932 |
Reactivity: | Human |
Applications: | Western blotting, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC54019 |
Reactivity: | Human |
Tested Applications: | WB, IP, ELISA |
Key Applications: | Western blotting, Immunoprecipitation |
Recommended Dilution: | WB 1:2000-1:20000, IP 150-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | 293F |
Cellular Location: | Nucleus |
This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human L3MBTL3 (NP_115814.1). |
Sequence: | MTESA SSTSG QEFDV FSVMD WKDGV GTLPG SDLKF RVNEF GALEV ITDEN EMENV KKATA TTTWM VPTAQ EAPTS PPSSR PVFPP AYWTS PPGCP TVFSE KTGMP FRLKD PVKVE GLQFC ENCCQ YGNVD ECLSG GNYCS QNCAR HIKDK DQKEE RDVEE DNEEE DPKCS RKKKP KLSLK ADTKE DGEER DDEME NKQDV RILRG SQRAR RKRRG DSAVL KQGLP PKGKK AWCWA SYLEE EKAVA VPAKL FKEHQ |
Synonyms: | MBT1, MBT-1 |
Calculated MW: | 88kDa |
Observed MW: | 100kDa |