KO Validated Antibodies 1

[KO Validated] L3MBTL3 Rabbit Polyclonal Antibody (CAB7289)

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SKU:
CAB7289
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse
Synonyms:
MBT1, MBT-1, L3MBTL3
Research Use:
Epigenetics and Nuclear Signaling
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Description

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[KO Validated] L3MBTL3 Antibody (CAB7289)

The [KO Validated] L3MBTL3 Antibody (CAB7289) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications. By binding to L3MBTL3, the antibody enables accurate detection and analysis of this protein in various cell types, facilitating studies in epigenetics and cancer research.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:[KO Validated] L3MBTL3 Antibody
SKU:CAB7289
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MTES ASST SGQE FDVF SVMD WKDG VGTL PGSD LKFR VNEF GALE VITD ENEM ENVK KATA TTTW MVPT AQEA PTSP PSSR PVFP PAYW TSPP GCPT VFSE KTGM PFRL KDPV KVEG LQFC ENCC QYGN VDEC LSGG NYCS QNCA RHIK DKDQ KEER DVEE DNEE EDPK CSRK KKPK LSLK ADTK EDGE ERDD EMEN KQDV RILR GSQR ARRK RRGD SAVL KQGL PPKG KKAW CWAS YLEE EKAV AVPA KLFK EHQ
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:2000 - 1:4000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MBT1, MBT-1, L3MBTL3
Positive Sample:Mouse lung
Cellular Localization:Nucleus.
Calculated MW:88kDa
Observed MW:100kDa

This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma.

Purification MethodAffinity purification
Gene ID84456
RRIDAB_2767830
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Mouse lung, using L3MBTL3 Rabbit pAb (CAB7289) at 1:4000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human breast cancer using L3MBTL3 Rabbit pAb (CAB7289) at dilution of 1:50 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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