Description
Product Name: | Ki67 Monoclonal Antibody |
Product Code: | CAB23722 |
Reactivity: | Human, Mouse, Rat |
Applications: | Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC57561 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | IHC-P, IF/ICC, ELISA |
Key Applications: | Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | IHC-P 1:100-1:500, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Cellular Location: | Chromosome, Nucleus, nucleolus |
Enables protein C-terminus binding activity. Involved in regulation of chromosome segregation and regulation of mitotic nuclear division. Located in chromosome; nuclear body; and nucleolus. Colocalizes with condensed chromosome. Implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Biomarker of several diseases, including Barrett's esophagus; autoimmune disease of musculoskeletal system (multiple); endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); and interstitial cystitis.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 2271-2370 of human Ki67 (NP_002408.3). |
Sequence: | PAGGD EKDMK AFMGT PVQKL DLPGN LPGSK RWPQT PKEKA QALED LAGFK ELFQT PGTDK PTTDE KTTKI ACKSP QPDPV DTPAS TKQRP KRNLR KADVE |
Synonyms: | KIA, MIB-, MIB-1, PPP1R105 |
Calculated MW: | 359kDa |
Observed MW: | Refer to figures |