Description
| Product Name: | Ki67 Monoclonal Antibody |
| Product Code: | CAB20018 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC5050-01 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IHC-P, IF/ICC, ELISA |
| Key Applications: | Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | IHC-P 1:100-1:500, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Chromosome, Nucleus, nucleolus |
| Customer Validation: | WB(Mus musculus)IHC(Homo sapiens)IF/ICC(Homo sapiens) |
Enables protein C-terminus binding activity. Involved in regulation of chromosome segregation and regulation of mitotic nuclear division. Located in chromosome; nuclear body; and nucleolus. Colocalizes with condensed chromosome. Implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Biomarker of several diseases, including Barrett's esophagus; autoimmune disease of musculoskeletal system (multiple); endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); and interstitial cystitis.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1200-1300 of human Ki67 (NP_002408.3). |
| Sequence: | LAGTL PGSKR QLQTP KEKAQ ALEDL AGFKE LFQTP GHTEE LVAAG KTTKI PCDSP QSDPV DTPTS TKQRP KRSIR KADVE GELLA CRNLM PSAGK AMHTP K |
| Synonyms: | KIA, MIB-, MIB-1, PPP1R105 |
| Calculated MW: | 359kDa |
| Observed MW: | Refer to figures |