KEAP1 Polyclonal Antibody (CAB21724)
- SKU:
- CAB21724
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | KEAP1 Polyclonal Antibody |
| Product Code: | CAB21724 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T |
| Cellular Location: | Cytoplasm, Nucleus |
| Customer Validation: | WB(Homo sapiens) |
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 320-510 of human KEAP1 (NP_036421.2). |
| Sequence: | RAPKV GRLIY TAGGY FRQSL SYLEA YNPSD GTWLR LADLQ VPRSG LAGCV VGGLL YAVGG RNNSP DGNTD SSALD CYNPM TNQWS PCAPM SVPRN RIGVG VIDGH IYAVG GSHGC IHHNS VERYE PERDE WHLVA PMLTR RIGVG VAVLN RLLYA VGGFD GTNRL NSAEC YYPER NEWRM ITAMN TIRSG A |
| Synonyms: | INrf2, KLHL19 |
| Calculated MW: | 70kDa |
| Observed MW: | 60-64kDa |
Related Products
![Anti-KEAP1 Antibody (CAB17061)[KO Validated]](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/44185/48930/anti-keap1-antibody-cab17061ko-validated__99861__62540.1706523733.jpg?c=1 "Anti-KEAP1 Antibody (CAB17061)[KO Validated]")
GATA3 Polyclonal Antibody
OverviewProduct Name:GATA3 Polyclonal AntibodyProduct Code:CAB21809Reactivity:MouseApplications:Western blotting
AMPKγ1 Polyclonal Antibody
OverviewProduct Name:AMPKγ1 Polyclonal AntibodyProduct Code:CAB22024Reactivity:Human, Mouse, RatApplications:Western blotting
NXPH1 Polyclonal Antibody
OverviewProduct Name:NXPH1 Polyclonal AntibodyProduct Code:CAB10770Reactivity:HumanApplications:Western blotting
Rv0222 Polyclonal Antibody
OverviewProduct Name:Rv0222 Polyclonal AntibodyProduct Code:CAB20742Reactivity:Mycobacterium tuberculosisApplications:Western blo