Description
Product Name: | [KD Validated] NUR77 Monoclonal Antibody |
Product Code: | CAB24016 |
Reactivity: | Human, Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC58221 |
Reactivity: | Human, Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, PC-3 |
Cellular Location: | Cytoplasm, Nucleus |
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human NUR77 (NP_002126.2) |
Sequence: | PSLAQ SPLKL FPSQA THQLG EGESY SMPTA FPGLA PTSPH LEGSG ILDTP VTSTK ARSGA PGGSE GRCAV CGDNA SCQHY GVRTC EGCKG FFKRT VQKNA K |
Synonyms: | HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77 |
Calculated MW: | 64kDa |
Observed MW: | 64kDa |