Description
| Product Name: | [KD Validated] NUR77 Monoclonal Antibody |
| Product Code: | CAB24016 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58221 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, PC-3 |
| Cellular Location: | Cytoplasm, Nucleus |
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human NUR77 (NP_002126.2) |
| Sequence: | PSLAQ SPLKL FPSQA THQLG EGESY SMPTA FPGLA PTSPH LEGSG ILDTP VTSTK ARSGA PGGSE GRCAV CGDNA SCQHY GVRTC EGCKG FFKRT VQKNA K |
| Synonyms: | HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77 |
| Calculated MW: | 64kDa |
| Observed MW: | 64kDa |