Description
Product Name: | [KD Validated] METTL14 Monoclonal Antibody |
Product Code: | CAB24396 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59147 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IP, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:1000-1:5000, IP 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Raji, PC-3, A549 |
Cellular Location: | Nucleus |
Enables mRNA binding activity. Contributes to mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity. Involved in mRNA metabolic process; negative regulation of hematopoietic progenitor cell differentiation; and positive regulation of translation. Located in nucleoplasm. Part of RNA N6-methyladenosine methyltransferase complex.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human METTL14 (NP_066012.1). |
Sequence: | MDSRL QEIRE RQKLR RQLLA QQLGA ESADS IGAVL NSKDE QREIA ETRET CRASY DTSAP NAKRK YLDEG ETDED KMEEY KDELE MQQDE ENLPY EEEIY KDSST FLKGT QSLNP HNDYC QHFVD TGHRP QNFIR DVGLA DRFEE YPKLR ELIRL KDELI AKSNT PPMYL QADIE AFDIR ELTPK FDVIL LEPPL EEYYR ETGIT ANEKC |
Synonyms: | hMETTL14 |
Calculated MW: | 52kDa |
Observed MW: | 65KDa |