Description
Product Name: | [KD Validated] Gelsolin Monoclonal Antibody |
Product Code: | CAB22184 |
Reactivity: | Human |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC56199 |
Reactivity: | Human |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, Hep G2 |
Cellular Location: | Cytoplasm, Cytoskeleton, Secreted |
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-782 of human Gelsolin (NP_000168.1). |
Sequence: | ATASR GASQA GAPQG RVPEA RPNSM VVEHP EFLKA GKEPG LQIWR VEKFD LVPVP TNLYG DFFTG DAYVI LKTVQ LRNGN LQYDL HYWLG NECSQ DESGA AAIFT VQLDD YLNGR AVQHR EVQGF ESATF LGYFK SGLKY KKGGV ASGFK HVVPN EVVVQ RLFQV KGRRV VRATE VPVSW ESFNN GDCFI LDLGN NIHQW CGSNS NRYER LKATQ VSKGI RDNER SGRAR VHVSE EGTEP EAMLQ VLGPK PALPA GTEDT AKEDA ANRKL AKLYK VSNGA GTMSV SLVAD ENPFA QGALK SEDCF ILDHG KDGKI FVWKG KQANT EERKA ALKTA SDFIT KMDYP KQTQV SVLPE GGETP LFKQF FKNWR DPDQT DGLGL SYLSS HIANV ERVPF DAATL HTSTA MAAQH GMDDD GTGQK QIWRI EGSNK VPVDP ATYGQ FYGGD SYIIL YNYRH GGRQG QIIYN WQGAQ STQDE VAASA ILTAQ LDEEL GGTPV QSRVV QGKEP AHLMS LFGGK PMIIY KGGTS REGGQ TAPAS TRLFQ VRANS AGATR AVEVL PKAGA LNSND AFVLK TPSAA YLWVG TGASE AEKTG AQELL RVLRA QPVQV AEGSE PDGFW EALGG KAAYR TSPRL KDKKM DAHPP RLFAC SNKIG RFVIE EVPGE LMQED LATDD VMLLD TWDQV FVWVG KDSQE EEKTE ALTSA KRYIE TDPAN RDRRT PITVV KQGFE PPSFV GWFLG WDDDY WSVDP LDRAM AELAA |
Synonyms: | ADF, AGEL |
Calculated MW: | 86kDa |
Observed MW: | 86kDa |