KCNK2 Polyclonal Antibody
- SKU:
- CAB10683
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | KCNK2 Polyclonal Antibody |
| Product Code: | CAB10683 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein, Multi-pass membrane protein |
This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 297-411 of human KCNK2 (NP_055032.1). |
| Sequence: | RVISK KTKEE VGEFR AHAAE WTANV TAEFK ETRRR LSVEI YDKFQ RATSI KRKLS AELAG NHNQE LTPCR RTLSV NHLTS ERDVL PPLLK TESIY LNGLT PHCAG EEIAV IENIK |
| Synonyms: | TREK, TPKC1, TREK1, K2p2.1, TREK-1, hTREK-1c, hTREK-1e |
| Calculated MW: | 47kDa |
| Observed MW: | Refer to figures |
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