KCNE3 Polyclonal Antibody
- SKU:
- CAB10706
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | KCNE3 Polyclonal Antibody |
| Product Code: | CAB10706 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Cell projection, Cytoplasm, Perikaryon, Single-pass type I membrane protein, dendrite |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KCNE3 (NP_005463.1). |
| Sequence: | METTN GTETW YESLH AVLKA LNATL HSNLL CRPGP GLGPD NQTEE RRASL PGRDD NSYMY ILFVM FLFAV TVGSL ILGYT RSRKV DKRSD PYHVY IKNRV |
| Synonyms: | HYPP, HOKPP, MiRP2, BRGDA6 |
| Calculated MW: | 12kDa |
| Observed MW: | Refer to figures |
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