Description
| Product Name: | KATNB1 Polyclonal Antibody |
| Product Code: | CAB21041 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse testis, Rat testis |
| Cellular Location: | centrosome, cytoplasm, cytosol, katanin complex, microtubule cytoskeleton, nucleus, plasma membrane, spindle, spindle pole |
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human KATNB1 (NP_005877.2). |
| Sequence: | SEPFP APPED DAATA KEAAK PSPAM DVQFP VPNLE VLPRP PVVAS TPAPK AEPAI IPATR NEPIG LKASD FLPAV KIPQQ AELVD EDAMS QIRKG HDTMC V |
| Synonyms: | KAT, LIS6 |
| Calculated MW: | 72kDa |
| Observed MW: | 72kDa |