JPH3 Polyclonal Antibody
- SKU:
- CAB10686
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | JPH3 Polyclonal Antibody |
| Product Code: | CAB10686 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Endoplasmic reticulum membrane, Peripheral membrane protein, Single-pass type IV membrane protein |
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansion from normally 6-28 repeats to 40-59 repeats in the 3' UTR of this gene have been associated with Huntington disease-like 2 (HDL2). This gene is a member of the junctophilin gene family. Alternatively spliced transcript variants have been described for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-727 of human JPH3 (NP_065706.2). |
| Sequence: | HFSRQ VSVDE ERGGD IQMLL EGRAG DCARS SWGEE QAGGS RGVRS GALRG GLLVD DFRTR GSGRK QPGNP KPRER RTESP PVFTW TSHHR ASNHS PGGSR LLELQ EEKLS NYRME MKPLL RMETH PQKRR YSKGG ACRGL GDDHR PEDRG FGVQR LRSKA QNKEN FRPAS SAEPA VQKLA SLRLG GAEPR LLRWD LTFSP PQKSL PVALE SDEEN GDELK SSTGS API |
| Synonyms: | JP3, HDL2, JP-3, TNRC22, CAGL237 |
| Calculated MW: | 81kDa |
| Observed MW: | Refer to figures |
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