IRAK4 Polyclonal Antibody
- SKU:
- CAB21779
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | IRAK4 Polyclonal Antibody |
| Product Code: | CAB21779 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:2000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, Mouse brain, Rat brain |
| Cellular Location: | Cytoplasm |
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human IRAK4 (NP_057207.2). |
| Sequence: | MNKPI TPSTY VRCLN VGLIR KLSDF IDPQE GWKKL AVAIK KPSGD DRYNQ FHIRR FEALL QTGKS PTSEL LFDWG TTNCT VGDLV DLLIQ NEFFA PASLL LPDAV PKTAN TLPSK EAITV QQKQM PFCDK DRTLM TPVQN LEQSY MPPDS SSPEN KSLEV SDTRF HSFSF YELKN VTNNF DERPI SVGGN KMGEG GFGVV |
| Synonyms: | IPD1, IMD67, REN64, IRAK-4, NY-REN-64 |
| Calculated MW: | 52kDa |
| Observed MW: | 55kDa |
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