Immuno-Oncology Discovery In Vivo Pack with Matched Isotype Controls (IVSP0006)
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- SKU:
- IVSP0006
- Product Type:
- In Vivo Sampler Pack
- Format:
- 1 mg per component, Low Endotoxin
- Reactivity:
- Mouse
- Antibody Type:
- Functional-Grade In Vivo Antibody
- Endotoxin Level:
- Low Endotoxin
- Pack Contents:
- PD-1 (CD279) [RMP1-14] / PD-L1 (B7-H1/CD274) [10F.9G2] / CTLA-4 (CD152) [9H10] / LAG-3 (CD223) [C9B7W] / CD8alpha (Ly-2) [2.43]
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Description
Immuno-Oncology Discovery In Vivo Pack with Matched Isotype Controls
A five-antibody discovery panel spanning the PD-1, PD-L1, CTLA-4 and LAG-3 checkpoints plus CD8alpha, with matched isotype controls. Each vial is a low-endotoxin (< 1.0 EU/mg), functional-grade in vivo monoclonal at the 1 mg size for preclinical dosing in mouse models. The pack bundles the target antibodies and the matched isotype controls your study design needs in one catalogue item, at a 5% discount to buying the vials separately.
Note: VEGF-A (B20-4.1.1) from the original spec is not currently in the catalogue and has been omitted.
| Product Code | Product / Target | Clone | Isotype | Size | Role |
| IVMB0037 | PD-1 (CD279) | RMP1-14 | Rat IgG2a, kappa | 1 mg | Target antibody |
| IVMB0095 | PD-L1 (B7-H1/CD274) | 10F.9G2 | Rat IgG2b, kappa | 1 mg | Target antibody |
| IVMB0047 | CTLA-4 (CD152) | 9H10 | Syrian Hamster IgG | 1 mg | Target antibody |
| IVMB0088 | LAG-3 (CD223) | C9B7W | Rat IgG1, kappa | 1 mg | Target antibody |
| IVMB0070 | CD8alpha (Ly-2) | 2.43 | Rat IgG2b | 1 mg | Target antibody |
| IVMB0198 | Rat IgG2a Isotype Control | – | Rat IgG2a | 1 mg | Matched isotype control (for PD-1 (CD279) [RMP1-14]) |
| IVMB0200 | Rat IgG2b Isotype Control | – | Rat IgG2b | 1 mg | Matched isotype control (for PD-L1 (B7-H1/CD274) [10F.9G2], CD8alpha (Ly-2) [2.43]) |
| IVMB0378 | Syrian Hamster IgG Isotype Control | – | Syrian Hamster IgG | 1 mg | Matched isotype control (for CTLA-4 (CD152) [9H10]) |
| IVMB0196 | Rat IgG1 Isotype Control | – | Rat IgG1 | 1 mg | Matched isotype control (for LAG-3 (CD223) [C9B7W]) |
| Pack Code: | IVSP0006 |
| Contents: | 5 target antibodies + 4 matched isotype controls = 9 × 1 mg vials |
| Format: | Low Endotoxin, functional grade, mouse reactivity |
| List Price: | £1431 GBP / €1431 EUR (sum of individual 1 mg list prices) |
| Pack Price (5% off): | £1359 GBP / €1359 EUR – save £72 / €72 |
| Storage: | 2–8°C up to one month; aliquot and store at -80°C for long term. Avoid repeated freeze-thaw. |
| Recommended for: | Immuno-oncology discovery, multi-checkpoint blockade, T-cell exhaustion, combination immunotherapy. |
| Reactivity: | Mouse |
| Application class: | In Vivo (depletion / blocking) |
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