Immune Checkpoint Recombinant Proteins

Human CLDN6 Recombinant Protein (mFc Tag)Description:Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and...

Human CLEC12A Recombinant Protein (His Tag)Description:This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein...

Human CLEC2D Recombinant Protein (hFc Tag)Description:This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and...

Human CS1 Recombinant Protein (hFc-His Tag)Description:SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319,...

Human CSF1R Recombinant Protein (His Tag)Description:The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and...

Human CSF2RA Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls...

Human CSPG4 Recombinant Protein (His Tag)Description:A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of...

Human CTLA-4 Recombinant Protein (hFc Tag)Description:This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein...

Human CTLA-4 Recombinant Protein (mFc-His Tag)Description:This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein...

Human CXC-R3 Recombinant Protein (hFc Tag)Description:This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g),...

Human CXC-R4 Recombinant Protein (hFc Tag)Description:This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on...

Human CXC-R5 Recombinant Protein (hFc Tag)Description:This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and...

Human CXCR2 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It...

Human DKK1 Recombinant Protein (hFc Tag)Description:This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich...

Human DKK2 Recombinant Protein (hFc Tag)Description:This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in...

Human DNAM-1 Recombinant Protein (mFc-His Tag)Description:This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the...

Human EGFR Recombinant Protein (His Tag)Description:The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for...

Human EPCAM Recombinant Protein (His Tag)Description:This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is...

Human EPHA2 Recombinant Protein (His Tag)Description:This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in...

Human EPHA3 Recombinant Protein (mFc-His Tag)Description:This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated...

Human FAP Recombinant Protein (His Tag)Description:The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed...

Human FCGR3A Protein (F176V), His Tag)Description:This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the...

Human FLT3 Ligand Recombinant Protein (mFc-His Tag)Description:FMS-like tyrosine kinase 3 ligand (Flt-3 Ligand) is also known as FL, Flt3L and FLT3LG, is an α-helical cytokine that promotes the...

Human FLT3 Recombinant Protein (hFc-His Tag)Description:Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3...

Human FN1 Recombinant Protein (hFc Tag)Description:This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface...

Human FOLR1 Recombinant Protein (His Tag)Description:The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced...

Human FOLR2 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of...

Human Galectin 9 Recombinant Protein (hFc Tag)Description:The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein...

Human Gastrin Recombinant Protein (hFc Tag)Description:Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin...

Human GDNF Recombinant Protein (hFc Tag)Description:This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various...

Human GITR Ligand Recombinant Protein (mFc-His Tag)Description:The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand...

Human GITR Recombinant Protein (hFc-His Tag)Description:This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell...

Human GITR Recombinant Protein (mFc-His Tag)Description:This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell...

Human GPA33 Recombinant Protein (hFc Tag)Description:The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading...

Human GPC1 Recombinant Protein (hFc Tag)Description:Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate...

Human GPRC5D Recombinant Protein (hFc-His Tag)Description:The protein encoded by this gene is a member of the G protein-coupled receptor family; however, the specific function of this gene has not...

Human HBL Recombinant Protein (hFc Tag)Description:The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product...

Human Her2 Recombinant Protein (His Tag)Description:This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding...

Human HER3 Recombinant Protein (His Tag)Description:This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a...

Human HGF Recombinant Protein (hFc Tag)Description:This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous...

Human HVEM Recombinant Protein (His Tag)Description:This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways...

Human ICAM-1 Recombinant Protein (mFc Tag)Description:This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to...

Human ICOS Recombinant Protein (hFc Tag)Description:The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in...

Human ICOS Recombinant Protein (mFc-His Tag)Description:The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role...

Human IFNAR1 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta...

Human IGF-1R Recombinant Protein (hFc Tag)Description:This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor...

Human IgG1-Fc Recombinant ProteinDescription:IGHG1 (Immunoglobulin Heavy Constant Gamma 1 (G1m Marker)) is a Protein Coding gene. Diseases associated with IGHG1 include Leukemia, Chronic...

Human IL-7RA Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma...

Human IL13RA1 Recombinant Protein (His Tag)Description:The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a...

Human IL15RA Recombinant Protein (hFc Tag)Description:This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two...

Human IL17RA Recombinant Protein (His Tag)Description:Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of...

Human IL18 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates...

Human IL18R1 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds...

Human IL1A Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various...

Human IL1B Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a...

Human IL1R1 Recombinant Protein (hFc Tag)Description:This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1...

Human IL20 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal...

Human IL21 Recombinant Protein (hFc Tag)Description:This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both...

Human IL2RA Recombinant Protein (His Tag)Description:The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity...

Human IL2RB Recombinant Protein (His Tag)Description:The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind...

Human IL4RA Recombinant Protein (hFc Tag)Description:This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to...

Human IL5 Recombinant Protein (hFc Tag)Description:This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major...

Human IL5 Recombinant Protein (His Tag)Description:This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major...

Human IL5RA Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand...

Human IL5RA Recombinant Protein (His Tag)Description:The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand...

Human IL6 Recombinant Protein (mFc-His Tag)Description:This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be...

Human IL6R Recombinant Protein (hFc Tag)Description:This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth...

Human IL6R Recombinant Protein (His Tag)Description:This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth...

Human KLRC1 Recombinant Protein (hFc Tag)Description:Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They...

Human KLRG1 Recombinant Protein (hFc Tag)Description:Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They...

Human KRAS Recombinant Protein (hFc Tag)Description:This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A...

Human LAG3 Recombinant Protein (hFc Tag)Description:Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The...

Human LAG3 Recombinant Protein (His Tag)Description:Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The...

Human LGALS3 Recombinant Protein (hFc Tag)Description:This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for...

Human LIGHT Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a...

Human LRRC32 Recombinant Protein (hFc Tag)Description:This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are...

Human MASP2 Recombinant Protein (hFc Tag)Description:This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A...

Human MICA Recombinant Protein (His Tag)Description:This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the...

Human MICB Recombinant Protein (His Tag)Description:This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic...

Human MSLN(296-580) Recombinant Protein (mFc-His Tag)Description:This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating...

Human MUC1 Recombinant Protein (hFc Tag)Description:This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in...

Human MUC1 Recombinant Protein (His Tag)Description:This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in...

Human NCR1 Recombinant Protein (hFc Tag)Description:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis...

Human NECTIN4 Recombinant Protein (hFc Tag)Description:This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like...

Human NKG2D Recombinant Protein (mFc Tag)Description:Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They...

Human NKp30 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein...

Human NRG1 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and...

Human NTB-A Recombinant Protein (mFc-His Tag)Description:The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This...

Human OX40 Recombinant Protein (hFc-His Tag)Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its...

Human OX40L Recombinant Protein (mFc-His Tag)Description:This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell...

Human PD-1 Recombinant Protein ( His Tag)Description:This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in...

Human PD-1 Recombinant Protein (hFc-His Tag)Description:This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in...

Human PD-1 Recombinant Protein (mFc-His Tag)Description:This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in...

Human PD-L1 Recombinant Protein (mFc-His Tag)Description:This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B...

Human PDL2 Recombinant Protein (His Tag)Description:Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1...

Human PMEL Recombinant Protein (hFc Tag)Description:This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the...

Human PROM1 Recombinant Protein (hFc Tag)Description:This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem...

Human PSCA Recombinant Protein (hFc Tag)Description:This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is...

Human PSMA Recombinant Protein (hFc Tag)Description:This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on...

Human PSMA Recombinant Protein (His Tag)Description:This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on...