Description
| Product Name: | IL9 Monoclonal Antibody |
| Product Code: | CAB24007 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62039 |
| Reactivity: | Human |
| Tested Applications: | WB, FC, FC(Intra), ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000, FC(Intra) 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T(Transfection) |
| Cellular Location: | Secreted |
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to aminoacids 19-144 of human IL9(NP_000581.1). |
| Sequence: | QGCPT LAGIL DINFL INKMQ EDPAS KCHCS ANVTS CLCLG IPSDN CTRPC FSERL SQMTN TTMQT RYPLI FSRVK KSVEV LKNNK CPYFS CEQPC NQTTA GNALT FLKSL LEIFQ KEKMR GMRGK I |
| Synonyms: | P40, HP40, IL-9 |
| Calculated MW: | 16kDa |
| Observed MW: | 19kDa |