Description
| Product Name: | IKKβ Monoclonal Antibody |
| Product Code: | CAB22425 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC0085 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:2000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, Membrane raft, Nucleus |
The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IKKβ (O14920). |
| Sequence: | MSWSP SLTTQ TCGAW EMKER LGTGG FGNVI RWHNQ ETGEQ IAIKQ CRQEL SPRNR ERWCL EIQIM RRLTH PNVVA ARDVP EGMQN LAPND LPLLA MEYCQ |
| Synonyms: | IKK2, IKKB, IMD15, IMD15A, IMD15B, NFKBIKB, IKK-beta |
| Calculated MW: | 87kDa |
| Observed MW: | Refer to figures |