Description
Product Name: | IFNGR1 Monoclonal Antibody |
Product Code: | CAB21912 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC0662 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:2000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, 293T, BxPC-3, Mouse liver, Mouse spleen, Mouse thymus, Rat liver |
Cellular Location: | Membrane, Single-pass type I membrane protein |
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 390-489 of human IFNGR1 (P15260). |
Sequence: | GSIAL NSYHS RNCSE SDHSR NGFDT DSSCL ESHSS LSDSE FPPNN KGEIK TEGQE LITVI KAPTS FGYDK PHVLV DLLVD DSGKE SLIGY RPTED SKEFS |
Synonyms: | CD119, IFNGR, IMD27A, IMD27B |
Calculated MW: | 54kDa |
Observed MW: | 40-100kDa |