Human XG Recombinant Protein (RPPB5157)

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SKU:
RPPB5157
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P55808

Description

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Product Name:Human XG Recombinant Protein
Product Code:RPPB5157
Size:10µg
Species:Human
Target:XG
Synonyms:Glycoprotein Xg isoform 1 precursor, PBDX, Glycoprotein Xg, PBDX, XG.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:XG protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSQRDFDLA DALDDPEPTK KPNSDIYPKP KPPYYPQPEN PDSGGNIYPR PKPRPQPQPG NSGNSGGYFN DVDRDDGRYP PRPRPRPPAG GGGGGYSSYG NSDNTHGGDH HSTYGNPEGN MVAK

XG is the XG blood group antigen, and is at the pseudoautosomal boundary on the short (p) arm of chromosome X. The three 5' exons are located in the pseudoautosomal area and the remaining exons within the X-specific end. A shorted copy of XG is found on the Y chromosome at the pseudoautosomal boundary. XG is transcribed, although not expected to make a Y-chromosome specific gene product.

XG Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (22-142a.a) and having a molecular mass of 15.5kDa. XG is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:XG: the XG blood group antigen, and is located at the pseudoautosomal boundary on the short (p) arm of chromosome X. The three 5' exons reside in the pseudoautosomal region and the remaining exons within the X-specific end. A truncated copy of this gene is found on the Y chromosome at the pseudoautosomal boundary. It is transcribed, but not expected to make a Y-chromosome specific gene product. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]Protein type: Membrane protein, integral; Cell surfaceChromosomal Location of Human Ortholog: Xp22.33Cellular Component: integral to plasma membraneDisease: Blood Group, Xg System
UniProt Protein Details:
NCBI Summary:This gene encodes the XG blood group antigen, and is located at the pseudoautosomal boundary on the short (p) arm of chromosome X. The three 5' exons reside in the pseudoautosomal region and the remaining exons within the X-specific end. A truncated copy of this gene is found on the Y chromosome at the pseudoautosomal boundary. It is transcribed, but not expected to make a Y-chromosome specific gene product. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
UniProt Code:P55808
NCBI GenInfo Identifier:213688346
NCBI Gene ID:7499
NCBI Accession:NP_001135391.1
UniProt Secondary Accession:P55808,Q496N8, Q496N9, Q496P0, Q71BZ5, E9PCH1
UniProt Related Accession:P55808
Molecular Weight:21,439 Da
NCBI Full Name:glycoprotein Xg isoform 2
NCBI Synonym Full Names:Xg blood group
NCBI Official Symbol:XG��
NCBI Official Synonym Symbols:PBDX��
NCBI Protein Information:glycoprotein Xg
UniProt Protein Name:Glycoprotein Xg
UniProt Synonym Protein Names:Protein PBDX
Protein Family:Glycoprotein
UniProt Gene Name:XG��
UniProt Entry Name:XG_HUMAN
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