Cell Biology Recombinant Proteins

Human VCL/Vinculin Recombinant Protein (RPES0662)

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SKU:
RPES0662
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Biology

Description

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Human VCL/Vinculin Recombinant Protein

Vinculin (VCL) is a cytoskeletal protein that is closely related to both cell-matrix interactions and cell-cell junctions. VCL is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. This protein has multi-ligand properties and has been found to interact with a number of microfilament associated proteins, such as talin, a-actinin, and paxillin, which reportedly bind to either the head or tail domains of vinculin.

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