Cell Biology Recombinant Proteins

Human VCL/Vinculin Recombinant Protein (RPES0662)

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SKU:
RPES0662
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Biology

Description

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Human VCL/Vinculin Recombinant Protein

Vinculin (VCL) is a cytoskeletal protein that is closely related to both cell-matrix interactions and cell-cell junctions. VCL is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. This protein has multi-ligand properties and has been found to interact with a number of microfilament associated proteins, such as talin, a-actinin, and paxillin, which reportedly bind to either the head or tail domains of vinculin.

Product Name:Human VCL/Vinculin Recombinant Protein (RPES0662)
Product Code:RPES0662
Size:20µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:Vinculin, Metavinculin, VCL,CMD1W,CMH15,HEL114,MV,MVCL
Accession:P18206-2
Sequence:Met 1-Gln 1066
Fusion tag:C-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human VCL (P18206-2) (Met 1-Gln 1066) was expressed, fused with a polyhistidine tag at the C-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:118 kDa
AP Mol Mass:115 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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