Human Vaspin/SerpinA12 Recombinant Protein (RPES5075)
- SKU:
- RPES5075
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human Vaspin/SerpinA12 Recombinant Protein
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets; nine ?-helices; and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity; insulin resistance; and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.
| Product Name: | Human Vaspin/SerpinA12 Recombinant Protein (RPES5075) |
| Product Code: | RPES5075 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Serpin A12, OL-64, Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, Visceral Adipose-Specific Serpin, SERPINA12 |
| Accession: | Q8IW75 |
| Sequence: | Leu21-Lys414 |
| Fusion tag: | N-GST |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Serpin A12 is produced by our E.coli expression system and the target gene encoding Leu21-Lys414 is expressed with a GST tag at the N-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 71.4 kDa |
| AP Mol Mass: | 72 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 50mM TrisHCl; 160mM NaCl; 0.2mM PMSF; 1mM DTT; 10% Glycerine; pH 7.2 . |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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