Human VAMP5 Recombinant Protein (RPPB5107)
- SKU:
- RPPB5107
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- O95183
Description
| Product Name: | Human VAMP5 Recombinant Protein |
| Product Code: | RPPB5107 |
| Size: | 20µg |
| Species: | Human |
| Target: | VAMP5 |
| Synonyms: | VAMP5, Vesicle-associated membrane protein 5, VAMP-5, Myobrevin, HSPC191. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The VAMP5 protein solution contains 20mM Tris-HCl, pH-8, 100mM NaCl, 1mM DTT and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAG IELERCQQQA NEVTEIMRNN FGKVLERGVK LAELQQRSDQ LLDMSSTFNK TTQNLAQKKC WENIRYRIC |
VAMP5 is part of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. VAMP5 is involved is vesicle trafficking events that are associated with myogenesis.
VAMP5 produced in E.Coli is a single,non-glycosylated polypeptide chain containing 109 amino acids (1-72 a.a.) and having a molecular mass of 12.7 kDa.VAMP5 is fused to 37 amino acids His Tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | VAMP5: May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking. Belongs to the synaptobrevin family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 2p11.2 Cellular Component: SNARE complex; synaptic vesicle; cytoplasmic vesicle membrane; cell surface; perinuclear region of cytoplasm; integral to plasma membrane; late endosome; plasma membrane; trans-Golgi network Molecular Function:SNAP receptor activity; SNARE binding Biological Process: vesicle fusion; muscle development; skeletal muscle development; exocytosis; neurotransmitter secretion; Golgi to plasma membrane protein transport; cell differentiation |
| NCBI Summary: | Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95183 |
| NCBI GenInfo Identifier: | 5730112 |
| NCBI Gene ID: | 10791 |
| NCBI Accession: | NP_006625.1 |
| UniProt Secondary Accession: | O95183,Q9P0T2, |
| UniProt Related Accession: | O95183 |
| Molecular Weight: | 12,805 Da |
| NCBI Full Name: | vesicle-associated membrane protein 5 |
| NCBI Synonym Full Names: | vesicle-associated membrane protein 5 |
| NCBI Official Symbol: | VAMP5�� |
| NCBI Protein Information: | vesicle-associated membrane protein 5; VAMP-5; myobrevin |
| UniProt Protein Name: | Vesicle-associated membrane protein 5 |
| UniProt Synonym Protein Names: | Myobrevin |
| Protein Family: | Vesicle-associated membrane protein |
| UniProt Gene Name: | VAMP5�� |
| UniProt Entry Name: | VAMP5_HUMAN |
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