Signal Transduction Recombinant Proteins

Human UCHL1/PGP9.5 Recombinant Protein (RPES1862)

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SKU:
RPES1862
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Signal Transduction

Description

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Human UCHL1/PGP9.5 Recombinant Protein

Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 (UCHL1) belongs to the Peptidase C12 family. UCHL1 is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. UCHL1 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. UCHL1 is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. UCHL1 also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer of UCHL1 may have ATP-independent ubiquitin ligase activity.

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