Signal Transduction Recombinant Proteins
Human UCHL1/PGP9.5 Recombinant Protein (RPES1862)
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- RPES1862
Description
system_update_altDatasheet
Human UCHL1/PGP9.5 Recombinant Protein
Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 (UCHL1) belongs to the Peptidase C12 family. UCHL1 is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. UCHL1 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. UCHL1 is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. UCHL1 also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer of UCHL1 may have ATP-independent ubiquitin ligase activity.
| Product Name: | Human UCHL1/PGP9.5 Recombinant Protein (RPES1862) |
| Product Code: | RPES1862 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1, UCH-L1, Neuron Cytoplasmic Protein 9.5, PGP 9.5, PGP9.5, Ubiquitin Thioesterase L1, UCHL1,HEL-117,NDGOA,PARK5,Uch-L1 |
| Accession: | P09936 |
| Sequence: | Met 1-Ala223 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 is produced by our E.coli expression system and the target gene encoding Met1-Ala223 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 25.9 kDa |
| AP Mol Mass: | 26 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 250mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Signal Transduction |
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