Epigenetics & Nuclear Signaling Recombinant Proteins
Human UBE2T Recombinant Protein (RPES2090)
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- SKU:
- RPES2090
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Epigenetics & Nuclear Signaling
Description
system_update_altDatasheet
Human UBE2T Recombinant Protein
Ubiquitin-Conjugating Enzyme E2 T (UBE2T) is a ligase that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2T accepts the ATP-dependent ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro; UBE2T is able to catalyze polyubiquitination using all 7 ubiquitin Lys residues; but may prefer 'Lys-11'-; 'Lys-27'-; 'Lys-48'- and 'Lys-63'-linked polyubiquitination. UBE2T is an important factor of the Faconi anemia pathway of DNA damage repair and; upon self-inactivation; may negatively regulate the Faconi pathway.
| Product Name: | Human UBE2T Recombinant Protein (RPES2090) |
| Product Code: | RPES2090 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Ubiquitin-Conjugating Enzyme E2 T, Cell Proliferation-Inducing Gene 50 Protein, Ubiquitin Carrier Protein T, Ubiquitin-Protein Ligase T, UBE2T |
| Accession: | Q9NPD8 |
| Sequence: | Met 1-Val197 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Ubiquitin-Conjugating Enzyme E2 T is produced by our E.coli expression system and the target gene encoding Met1-Val197 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 24.7 kDa |
| AP Mol Mass: | 25 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 50mM HEPES; 150mM NaCl; 2mM DTT; 10% Glycerol; pH 7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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