Epigenetics & Nuclear Signaling Recombinant Proteins

Human UBE2A Recombinant Protein (RPES1907)

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SKU:
RPES1907
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Epigenetics & Nuclear Signaling

Description

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Human UBE2A Recombinant Protein

Protein ubiquitination is an important cell function for targeting aberrant or short-lived proteins for degradation. The three classes of enzymes that contribute to ubiquitination are ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. UBE2A encodes an E2 ubiquitin-conjugating enzyme. UBE2A enzyme activity is needed for post-replicative DNA damage repair and may be involved in transcriptional regulation. UBE2A is associated with cognitive disability due to alternative splicing. Because of various splicing, there are many transcript variants. UBE2A is associated with a variety of intellectual developmental disorders, X-linked syndromic, nascimento type, and Kaufman oculocerebrofacial syndrome. Protein metabolism and Class I MHC-mediated antigen processing and presentation are two of the UBE2A-interacting pathways. Human UBE2A Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

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