Signal Transduction Recombinant Proteins

Human UBA5 Recombinant Protein (RPES2231)

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SKU:
RPES2231
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Signal Transduction

Description

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Human UBA5 Recombinant Protein

UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. UBA5 is located primarily in cytoplasm, while it generally localizes to the nucleus in presence of SUMO2.

Product Name:Human UBA5 Recombinant Protein (RPES2231)
Product Code:RPES2231
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Ubiquitin-like modifier-activating enzyme 5, ThiFP1, UFM1-activating enzyme, Ubiquitin-activating enzyme E1 domain-containing protein 1, UBE1DC1, UBA5
Accession:Q9GZZ9
Sequence:Met 1-Met404
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Ubiquitin-fold Modifier 1 Activating Enzyme is produced by our E.coli expression system and the target gene encoding Met1-Met404 is expressed with a 6His tag at the N-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:47.0 kDa
AP Mol Mass:14&40-60 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl,50mM NaCl,1mM DTT, 10% glycerol,pH 8.0 .
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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