Human TTC33 Recombinant Protein (RPPB5037)
- SKU:
- RPPB5037
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- O96033
Description
| Product Name: | Human TTC33 Recombinant Protein |
| Product Code: | RPPB5037 |
| Size: | 10µg |
| Species: | Human |
| Target: | TTC33 |
| Synonyms: | Tetratricopeptide Repeat Domain 33, Osmosis-Responsive Factor, Tetratricopeptide Repeat Protein 33, TPR Repeat Protein 33, OSRF. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The TTC33 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGS MASFGWK RKIGEKVSKV TSQQFEAEAA DEKDVVDNDE GNWLHAIKRR KEILLEGCAE KSKQLKDEGA SLAENKRYRE AIQKWDEALQ LTPNDATLYE MKSQVLMSLH EMFPAVHAAE MAVQQNPHSW ESWQTLGRAQ LGLGEIILAI RSFQVALHIY PMNPEIWKED LSWARTLQEQ QKVAQRIKKS EAPAEVTHFS PKSIPDYDFE SDEIVAVCAA IAEKEKTVSA NKTMVIVSAS GAIETVTEKE DGATPPDGSV FIKAR |
Tetratricopeptide repeat protein 33 (TTC33) is comprised of 3 TPR repeats.
TTC33 Human Recombinant produced in E. coli is a single polypeptide chain containing 285 amino acids (1-262) and having a molecular mass of 31.8 kDa.TTC33 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. |
| NCBI Summary: | Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O96033 |
| NCBI GenInfo Identifier: | 4758732 |
| NCBI Gene ID: | 4338 |
| NCBI Accession: | NP_004522 |
| UniProt Secondary Accession: | O96033,Q6IAI3, |
| UniProt Related Accession: | O96007,O96033 |
| Molecular Weight: | 25 kDa (224aa) confirmed by MALDI-TOF |
| NCBI Full Name: | molybdopterin synthase catalytic subunit large subunit MOCS2B |
| NCBI Synonym Full Names: | molybdenum cofactor synthesis 2 |
| NCBI Official Symbol: | MOCS2�� |
| NCBI Official Synonym Symbols: | MPTS; MCBPE; MOCO1; MOCODB�� |
| NCBI Protein Information: | molybdopterin synthase catalytic subunit; molybdopterin synthase sulfur carrier subunit |
| UniProt Protein Name: | Molybdopterin synthase catalytic subunit |
| UniProt Synonym Protein Names: | MOCO1-B; Molybdenum cofactor synthesis protein 2 large subunit |
| UniProt Gene Name: | MOCS2�� |
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