Description
| Product Name: | Human TRAPPC3 Recombinant Protein |
| Product Code: | RPPB5001 |
| Size: | 20µg |
| Species: | Human |
| Target: | TRAPPC3 |
| Synonyms: | Trafficking protein particle complex subunit 3, BET3, BET3 homolog, 1110058K12Rik. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The TRAPPC3 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM Nacl, 1mM DTT and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSRQANRGTE SKKMSSELFT LTYGALVTQL CKDYENDEDV NKQLDKMGFN IGVRLIEDFL ARSNVGRCHD FRETADVIAK VAFKMYLGIT PSITNWSPAG DEFSLILENN PLVDFVELPD NHSSLIYSNL LCGVLRGALE MVQMAVEAKF VQDTLKGDGV TEIRMRFIRR IEDNLPAGEE |
TRAPPC3 is a part of the TRAPP complex that takes part in connection of transport vesicles to the cis-Golgi membrane. Additionally, TRAPPC3 is involved in vesicular transport from endoplasmic reticulum to Golgi.
TRAPPC3 Human Recombinant produced in E. coli is a single polypeptide chain containing 200 amino acids (1-180) and having a molecular mass of 22.4kDa.TRAPPC3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | TRAPPC3: May play a role in vesicular transport from endoplasmic reticulum to Golgi. Belongs to the TRAPP small subunits family. BET3 subfamily. |
| UniProt Protein Details: | Protein type:Endoplasmic reticulum Chromosomal Location of Human Ortholog: 1p34.3 Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; Golgi apparatus; Golgi membrane Molecular Function:protein binding Biological Process: cellular protein metabolic process; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine |
| NCBI Summary: | This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. The encoded protein participates in the regulation of transport from the endoplasmic reticulum to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
| UniProt Code: | O43617 |
| NCBI GenInfo Identifier: | 20177833 |
| NCBI Gene ID: | 27095 |
| NCBI Accession: | O43617.1 |
| UniProt Secondary Accession: | O43617,A6NDN0, B2RDN2, D3DPS2, |
| UniProt Related Accession: | O43617 |
| Molecular Weight: | 15,005 Da |
| NCBI Full Name: | Trafficking protein particle complex subunit 3 |
| NCBI Synonym Full Names: | trafficking protein particle complex 3 |
| NCBI Official Symbol: | TRAPPC3�� |
| NCBI Official Synonym Symbols: | BET3�� |
| NCBI Protein Information: | trafficking protein particle complex subunit 3 |
| UniProt Protein Name: | Trafficking protein particle complex subunit 3 |
| UniProt Synonym Protein Names: | BET3 homolog |
| Protein Family: | Trafficking protein particle complex |
| UniProt Gene Name: | TRAPPC3�� |
| UniProt Entry Name: | TPPC3_HUMAN |