Description
| Product Name: | Human TPRKB Recombinant Protein |
| Product Code: | RPPB4995 |
| Size: | 10µg |
| Species: | Human |
| Target: | TPRKB |
| Synonyms: | TP53RK binding protein, PRPK-binding protein, PRPK (p53-related protein kinase)-binding protein, CGI-121. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The TPRKB solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 150mM NaCl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMQLTHQ LDLFPECRVT LLLFKDVKNA GDLRRKAMEG TIDGSLINPT VIVDPFQILV AANKAVHLYK LGKMKTRTLS TEIIFNLSPN NNISEALKKF GISANDTSIL IVYIEEGEKQ INQEYLISQV EGHQVSLKNL PEIMNITEVK KIYKLSSQEE SIGTLLDAII CRMSTKDVL |
TPRKB is a member of the CGI121/TPRKB family. TPRKB is localized to nucleus and cytoplasm and is ubiquitously expressed. TPRKB is known to cooperate with TP53RK/PRPK.
TPRKB Human Recombinant produced E. coli is a single polypeptide chain containing 199 amino acids (1-175) and having a molecular mass of 22.2kDa.TPRKB is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | TPRKB: Belongs to the CGI121/TPRKB family. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 2p24.3-p24.1Cellular Component: cytoplasm; cytosol; nucleusMolecular Function: protein binding; protein kinase bindingBiological Process: tRNA processing |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9Y3C4 |
| NCBI GenInfo Identifier: | 7705590 |
| NCBI Gene ID: | 51002 |
| NCBI Accession: | NP_057142.1 |
| UniProt Secondary Accession: | Q9Y3C4,Q8IWR6, Q8IWR7, Q9H3K4, D6W5H6 |
| UniProt Related Accession: | Q9Y3C4 |
| Molecular Weight: | 19,661 Da |
| NCBI Full Name: | EKC/KEOPS complex subunit TPRKB |
| NCBI Synonym Full Names: | TP53RK binding protein |
| NCBI Official Symbol: | TPRKB�� |
| NCBI Official Synonym Symbols: | CGI-121�� |
| NCBI Protein Information: | EKC/KEOPS complex subunit TPRKB; PRPK-binding protein; TP53RK-binding protein; PRPK (p53-related protein kinase)-binding protein |
| UniProt Protein Name: | EKC/KEOPS complex subunit TPRKB |
| UniProt Synonym Protein Names: | PRPK-binding protein; TP53RK-binding protein |
| Protein Family: | EKC/KEOPS complex |
| UniProt Gene Name: | TPRKB�� |
| UniProt Entry Name: | TPRKB_HUMAN |