Growth Factors & Cytokines Recombinant Proteins
Human TNFSF4/OX40L Recombinant Protein (RPES1007)
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- SKU:
- RPES1007
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Growth Factors & Cytokines
Description
system_update_altDatasheet
Human TNFSF4/OX40L Recombinant Protein
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells; T cells; dendritic cells and endothelial cells. OX40L binds to OX40 (CD134); a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional; it has been found association with systemic lupus erythematosus; no association with occurrence of atherosclerosis.
| Product Name: | Human TNFSF4/OX40L Recombinant Protein (RPES1007) |
| Product Code: | RPES1007 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Tumor necrosis factor ligand superfamily member 4,Glycoprotein Gp34,OX40 ligand,OX40L,TAX transcriptionally-activated glycoprotein 1,TNFSF4,CD252,TXGP1,CD134L,CD252,GP34,OX-40,TXGP1 |
| Accession: | P23510 |
| Sequence: | Gln51-Leu183 |
| Fusion tag: | N-6His |
| Activity: | Immobilized Human OX40-Fc(Cat: PKSH032844) at 2µg/ml(100 ?l/well) can bind Biotinylated Human OX40L-His. The ED50 of Human OX40L-His is 4.7 ug/ml . |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human OX40 Ligand is produced by our Mammalian expression system and the target gene encoding Gln51-Leu183 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 16.3 kDa |
| AP Mol Mass: | 25-28 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl; pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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