Human TNFSF4/OX40L Recombinant Protein (RPES0652)
- SKU:
- RPES0652
- Product Type:
- Recombinant Protein
- Species:
- Human
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Description
system_update_altDatasheet
Human TNFSF4/OX40L Recombinant Protein
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed on the surface of activated B cells;T cells;dendritic cells and endothelial cells. OX40L binds to OX40(CD134);a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional;it has been found association with systemic lupus erythematosus;no association with occurrence of atherosclerosis.
| Product Name: | Human TNFSF4/OX40L Recombinant Protein (RPES0652) |
| Product Code: | RPES0652 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Tumor necrosis factor ligand superfamily member 4,Glycoprotein Gp34,OX40 ligand,OX40L,TAX transcriptionally-activated glycoprotein 1,TNFSF4,CD252,TXGP1,CD134L,CD252,GP34,OX-40,TXGP1 |
| Accession: | P23510 |
| Sequence: | Gln51-Leu183 |
| Fusion tag: | C-mFc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human OX40L is produced by our Mammalian expression system and the target geneencoding Gln51-Leu183 is expressed with a mFc tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 42.2 kDa |
| AP Mol Mass: | 50-70 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |