Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed on the surface of activated B cells;T cells;dendritic cells and endothelial cells. OX40L binds to OX40(CD134);a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional;it has been found association with systemic lupus erythematosus;no association with occurrence of atherosclerosis.
Recombinant Human OX40L is produced by our Mammalian expression system and the target geneencoding Gln51-Leu183 is expressed with a mFc tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
42.2 kDa
AP Mol Mass:
50-70 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
system_update_altDatasheetHuman TNFSF4/OX40L Recombinant Protein OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an
system_update_altDatasheetHuman TNFSF4/OX40L Recombinant Protein Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on th
system_update_altDatasheetMouse TNFSF4/OX40L Recombinant Protein OX40 ligand (OX40L), also called CD252, is a single-pass type II membrane protein of the TNF/TNF receptor superfamily. OX40L is ex
system_update_altDatasheetCynomolgus TNFSF4/OX40L Recombinant Protein Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed