Human TLR4 ELISA Kit

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SKU:
HUFI00788
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O00206
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
TLR4, CD284, ARMD10, CD284 antigen, hTollhomolog of Drosophila toll, TOLL, toll-like receptor 4
Reactivity:
Human
Research Area:
Immunology

Description

Human TLR4 ELISA Kit

The TLR4 receptor recognizes LPS from Gram-negative bacteria and other bacterial cell wall components. This binding activates the receptor and triggers downstream signaling pathways, leading to inflammatory responses which include increased cytokine production, increased expression of adhesion molecules on endothelial cells, and activation of leukocytes such as neutrophils and macrophages. As such, TLR4 plays a key role in the immune system and is used as a marker for certain autoimmune diseases, such as Crohn's disease.

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