Cell Death Recombinant Proteins

Human TGFBR2 Recombinant Protein (RPES4049)

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SKU:
RPES4049
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Death

Description

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Human TGFBR2 Recombinant Protein

TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.

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