Immune Checkpoint Recombinant Proteins
Human TGFB1 Recombinant Protein (hFc Tag) (HDPT0164)
(No reviews yet)
Write a Review
- SKU:
- HDPT0164
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human TGFB1 Recombinant Protein (hFc Tag)
| Description: | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. |
| Product name: | Human TGFB1 Recombinant Protein (hFc Tag) |
| Synonyms: | CED, DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta |
| Type: | protein |
| Size: | 50 µg |
| Name: | TGFB1 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 90% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | N-Human Fc tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | hFc（Glu99-Ala330）+TGFB1（Ala279-Ser359） |
| Gene ID: | 7040 |
| Uniprot: | P01137 |
| Molecular Weight: | 38.9 kDa |
Related Products
Human Gastrin Recombinant Protein (hFc Tag) (HDPT0343)
Immune Checkpoint Recombinant Proteins
Human Gastrin Recombinant Protein (hFc Tag)Description:Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin...
Human IL5RA Recombinant Protein (hFc Tag) (HDPT0183)
Immune Checkpoint Recombinant Proteins
Human IL5RA Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand...
Human CD24 Recombinant Protein (hFc Tag) (HDPT0149)
Immune Checkpoint Recombinant Proteins
Human CD24 Recombinant Protein (hFc Tag)Description:This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to...
Human CD43 Recombinant Protein (hFc Tag) (HDPT0476)
Immune Checkpoint Recombinant Proteins
Human CD43 Recombinant Protein (hFc Tag)Description:This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of...
Human CD99 Recombinant Protein (hFc Tag) (HDPT0248)
Immune Checkpoint Recombinant Proteins
Human CD99 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane...
Human DKK2 Recombinant Protein (hFc Tag) (HDPT0434)
Immune Checkpoint Recombinant Proteins
Human DKK2 Recombinant Protein (hFc Tag)Description:This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in...
Human FOLR2 Recombinant Protein (hFc Tag) (HDPT0268)
Immune Checkpoint Recombinant Proteins
Human FOLR2 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of...
Human IL20 Recombinant Protein (hFc Tag) (HDPT0474)
Immune Checkpoint Recombinant Proteins
Human IL20 Recombinant Protein (hFc Tag)Description:The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal...
Human SIGLEC9 Recombinant Protein (hFc Tag) (HDPT0399)
Immune Checkpoint Recombinant Proteins
Human SIGLEC9 Recombinant Protein (hFc Tag)Description:Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic...