Human SUSD4 Recombinant Protein (RPES4998)

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SKU:
RPES4998
Product Type:
Recombinant Protein
Species:
Human

Description

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Human SUSD4 Recombinant Protein

SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical pathway of complement activation at the C3 convertase step. SUSD4 deficiency may cause autism or Fryns syndrome, both of which are genetic diseases with severe abnormal neurological development and/or functions.

Product Name:Human SUSD4 Recombinant Protein (RPES4998)
Product Code:RPES4998
Size:20µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:PRO222
Accession:Q5VX71-3
Sequence:Met 1-Phe290
Fusion tag:C-Fc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human SUSD4 (Q5VX71-3) (Met1-Phe290) was fused with Fc region of mouse IgG at the C-terminus.
Purity:> 85 % as determined by reducing SDS-PAGE.
Mol Mass:53.8 kDa
AP Mol Mass:67 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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