Immunology Recombinant Proteins
Human STAT1 Recombinant Protein (RPES1886)
- SKU:
- RPES1886
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immunology
Description
Human STAT1 Recombinant Protein
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. STAT1 can also form a homodimer termed IFN-gamma-activated factor (GAF) through tyrosine and serine phosphorylation; migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes; resulting in an antiviral cellular state. STAT1 is a transcription activator and signal transducer that regulates cellular responses to interferons. The cause of STAT1 deficiency total and familial candidiasis type 7 is a lack of the enzyme STAT1. Human STAT1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human STAT1 Recombinant Protein (RPES1886) |
| Product Code: | RPES1886 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Signal Transducer and Activator of Transcription 1-Alpha/Beta, Transcription Factor ISGF-3 Components p91/p84, STAT1, CANDF7,IMD31A,IMD31B,IMD31C,ISGF-3,STAT91 |
| Accession: | P42224-2 |
| Sequence: | Met 1-Val712 |
| Fusion tag: | |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Signal Transducer and Activator of Transcription 1 is produced by our E.coli expression system and the target gene encoding Met1-Val712 is expressed. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 83.3 kDa |
| AP Mol Mass: | 85 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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