Metabolism Recombinant Proteins

Human Sialidase/NEU Recombinant Protein (RPES4989)

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SKU:
RPES4989
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism

Description

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Human Sialidase/NEU Recombinant Protein

Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.

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