Developmental Biology Recombinant Proteins
Human Semaphorin 3A/SEMA3A Recombinant Protein (RPES5094)
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- SKU:
- RPES5094
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Developmental Biology
Description
system_update_altDatasheet
Human Semaphorin 3A/SEMA3A Recombinant Protein
emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent; inhibiting axonal outgrowth; or as a chemoattractive agent; stimulating the growth of apical dendrites. In both cases; the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines.
| Product Name: | Human Semaphorin 3A/SEMA3A Recombinant Protein (RPES5094) |
| Product Code: | RPES5094 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Semaphorin III, SEMA3A, SEMAD, Hsema-I, SEMA1, SemD, Semad, coll-1 , Hsema-III, Sema III |
| Accession: | Q14563 |
| Sequence: | Lys26-Phe546 |
| Fusion tag: | N-His-Flag |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Semaphorin 3A is produced by our Mammalian expression system and the target gene encoding Lys26-Phe546 is expressed with a 6His-Flag tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 61.3 kDa |
| AP Mol Mass: | 70-75 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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