Human SCO1/SCOD1 Recombinant Protein (RPES3346)

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SKU:
RPES3346
Product Type:
Recombinant Protein
Species:
Human

Description

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Human SCO1/SCOD1 Recombinant Protein

Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos). SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4D). A disorder of the mitochondrial respiratory chain has heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.

Product Name:Human SCO1/SCOD1 Recombinant Protein (RPES3346)
Product Code:RPES3346
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Protein SCO1 Homolog Mitochondrial, SCO1, SCOD1
Accession:O75880
Sequence:Gly132-Ser300
Fusion tag:N-GST
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Protein SCO1 Homolog Mitochondrial is produced by our E.coli expression system and the target gene encoding Gly132-Ser300 is expressed with a GST tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:20.1 kDa
AP Mol Mass:19 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 50mM PB, 1mM DTT, pH 7.2.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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