Human RPS12 Recombinant Protein (RPPB4514)

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SKU:
RPPB4514
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P25398

Description

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Product Name:Human RPS12 Recombinant Protein
Product Code:RPPB4514
Size:20µg
Species:Human
Target:RPS12
Synonyms:S12, 40S ribosomalprotein S12.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:RPS12 protein solution (0.25mg/ml) contains 20mM Tris-HClbuffer, (pH 8.0), 0.15M NaCl, and 30% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAEEGIA AGGVMDVNTA LQEVLKTALI HDGLARGIRE AAKALDKRQAHLCVLASNCD EPMYVKLVEA LCAEHQINLI KVDDNKKLGE WVGLCKIDRE GKPRKVVGCS CVVVKDYGKESQAKDVIEEY FKCKK

RPS12 is aribosomal protein which is a part of the 40S subunit. RPS12 is a member of theS12E family of ribosomal proteins. RPS12 placed in the cytoplasm.RPS12 proteins existas multiple processed pseudogenes which are scattered throughout the genome.

RPS12 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 155 amino acids (1-132 a.a.) andhaving a molecular mass of 16.9kDa.RPS12 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

UniProt Protein Function:RPS12: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Translation

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: cytosol; membrane

Molecular Function:structural constituent of ribosome

Biological Process: cellular protein metabolic process; gene expression; mRNA catabolic process, nonsense-mediated decay; selenium metabolic process; selenocysteine metabolic process; SRP-dependent cotranslational protein targeting to membrane; translation; translational elongation; translational initiation; translational termination; viral infectious cycle; viral reproduction; viral transcription

NCBI Summary:Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Code:P25398
NCBI GenInfo Identifier:224471878
NCBI Gene ID:6206
NCBI Accession:P25398.3
UniProt Secondary Accession:P25398,Q76M58,
UniProt Related Accession:P25398
Molecular Weight:14,515 Da
NCBI Full Name:40S ribosomal protein S12
NCBI Synonym Full Names:ribosomal protein S12
NCBI Official Symbol:RPS12��
NCBI Official Synonym Symbols:S12��
NCBI Protein Information:40S ribosomal protein S12
UniProt Protein Name:40S ribosomal protein S12
Protein Family:Ribosomal protein
UniProt Gene Name:RPS12��
UniProt Entry Name:RS12_HUMAN
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