Human RPS10 Recombinant Protein (RPPB4513)
- SKU:
- RPPB4513
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P46783
Description
| Product Name: | Human RPS10 Recombinant Protein |
| Product Code: | RPPB4513 |
| Size: | 20µg |
| Species: | Human |
| Target: | RPS10 |
| Synonyms: | DBA9, S10, 40S ribosomal protein S10, RPS10. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | RPS10 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMLMPKKN RIAIYELLFK EGVMVAKKDV HMPKHPELAD KNVPNLHVMK AMQSLKSRGY VKEQFAWRHF YWYLTNEGIQ YLRDYLHLPP EIVPATLRRS RPETGRPRPK GLEGERPARL TRGEADRDTY RRSAVPPGAD KKAEAGAGSA TEFQFRGGFG RGRGQPPQ |
Ribosomes (the organelles that catalyze protein synthesis) consist of a small 40S subunit and a large 60S subunit. Jointly these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS10 which is is located in the cytoplasm and a part of the S10E family of ribosomal proteins, is a ribosomal protein that is a component of the 40S subunit. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found.
RPS10 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 188 amino acids (1-165 a.a) and having a molecular mass of 21kDa. RPS10 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RPS10: a ribosomal protein of the S10E family. Located in the cytoplasm and nucleus. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein is a component of the 40S subunit. |
| UniProt Protein Details: | Protein type:Nucleolus; Ribosomal; Translation; RNA-binding Chromosomal Location of Human Ortholog: 6p21.31 Cellular Component: focal adhesion; membrane; cytoplasm; nucleolus; ribosome; cytosol Molecular Function:protein binding Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translational elongation; viral reproduction; translation; translational initiation; mRNA catabolic process, nonsense-mediated decay; gene expression; viral transcription; viral infectious cycle; translational termination Disease: Diamond-blackfan Anemia 9 |
| NCBI Summary: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3).[provided by RefSeq, Feb 2011] |
| UniProt Code: | P46783 |
| NCBI GenInfo Identifier: | 1173177 |
| NCBI Gene ID: | 6204 |
| NCBI Accession: | P46783.1 |
| UniProt Secondary Accession: | P46783,Q5TZC0, B2R4E3, |
| UniProt Related Accession: | P46783 |
| Molecular Weight: | 165 |
| NCBI Full Name: | 40S ribosomal protein S10 |
| NCBI Synonym Full Names: | ribosomal protein S10 |
| NCBI Official Symbol: | RPS10�� |
| NCBI Official Synonym Symbols: | S10; DBA9�� |
| NCBI Protein Information: | 40S ribosomal protein S10 |
| UniProt Protein Name: | 40S ribosomal protein S10 |
| Protein Family: | Ribosomal protein |
| UniProt Gene Name: | RPS10�� |
| UniProt Entry Name: | RS10_HUMAN |
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